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Acute symptoms such as fatigue may improve within days, whilst neurological symptoms like paraesthesia typically require weeks to months of treatment

Specificity of staining was confirmed by staining with a rat IgG (6-001-F, R&D Systems, Bio-Techne), a Rabbit IgG (ab27478, Abcam) or a mouse IgG1, kappa (Abcam, ab18443) isotype controls

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The COA reports HPLC purity (99%), mass spectrometry identity confirmation, visual appearance, residual solvents, and moisture content for the exact lot shipped

When the body can't absorb nutrients, a deficiency may result