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Aichler M, Borgmann D, Krumsiek J, Buck A, MacDonald PE, Fox JEM, et al

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Heres the critical point: as we age, our natural levels of NAD+ decline significantly, by as much as 50% by the time we reach middle age

Both are sterile water preparations, but they serve different purposes: Sterile water without preservative is single-use by design once the seal is broken, the sterility is compromised because there's no preservative to resist contamination