Long-Term Safety Considerations When using semaglutide for an extended period, its essential to consider the treatments long-term safety
Wegovy commonly causes nausea, particularly during dose escalation, whilst stimulants can cause gastrointestinal upset in some individuals
Sexual Function Research MT-IIs activity at MC4R has been explored in the context of sexual arousal pathways, particularly in animal models and early human studies
More widespread use of SGLT2i in type 1 diabetes will necessitate implementation of strategies to assess and mitigate DKA risk, including preventative measures, patient education and continuous ketone monitoring, as well as a better understanding of the potential benefits for clinical cardiorenal outcomes, especially in high-risk populations such as people with CKD (Table 2) [46, 47]
Intensive glucose control and macrovascular outcomes in type 2 diabetes
For clinicians, staying informed about evolving regulations will be essential over the next several years