Mood and appetite, he explained, are closely related (think of stressful eating or eating when we are sad, comfort food), and a benefit of [GLP-1 drugs] is that they help control appetite and satiety, which allows patients to make better meal choices and become healthier. So, the modest improvement in depression seen in the study may be related to weight loss, improved blood sugars, [fewer diabetes] symptoms, and likely an overall sense of patients getting healthier, Splenser hypothesized
These weight loss medications work by mimicking the action of the glucagon-like peptide-1 hormone to regulate blood sugar levels and promote weight loss
It represents a novel class of medications known as dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonists
Stimulation of GLP-1R with exendin-4 in the PBN reduces food intake and therefore decreases body weight in rats
584(2): 15765 Bhuiyan AK, Jackson S, Turnbull DM, et al
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