This is a concern that applies to all significant weight loss interventions, not just tirzepatide, but it becomes more relevant as the magnitude of weight loss increases
In terms of therapeutic utility, insulin is problematic as chronic administration in non-diabetics has significant risk
Mol Med 2008;14(3-4):175-183
In hair research, the peptide is investigated for its effects on follicle size and growth cycles, partly through reducing follicle sensitivity to dihydrotestosterone (DHT) and enhancing scalp circulation and dermal papilla cell activation
Lancet ;398(10317): 2160-2172 View at Publisher | View at Google Scholar Frias JP, Deenadayalan S, Erichsen L, Knop FK, Lingvay I, et al
Statistical modeling was used to analyze the association between GLP-1 exposure and breast cancer incidence