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When to Prioritize B12 : Using Vitamin B12 is especially important for individuals at higher risk of deficiencysuch as older adults, vegans, or those with gastrointestinal conditionsto support their bodys response to semaglutide

use caution in Lebers hereditary optic neuropathy and discuss risks if youve had B6-related neuropathy or severe kidney disease

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Pyridoxine (B) in high doses is known to interact with certain drugs: it can reduce the therapeutic efficacy of levodopa by increasing peripheral conversion of levodopa to dopamine (vitamin B speeds up decarboxylation)

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