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Effective management of diarrhoea during retatrutide treatment begins with dietary and lifestyle modifications, which are generally the first-line approach for gastrointestinal side effects associated with incretin-based therapies

That said, here are some groups of people who are typically not candidates for semaglutide or advised to use it with caution: History of Pancreatitis Individuals with a history of pancreatitis, which is inflammation of the pancreas, should avoid semaglutide due to the potential risk of exacerbating the condition

Lancet 402 , 613626 (2023)

In the above studies, patients only experienced sustained weight loss by pairing these medications with dietary and exercise changes

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Most people report that it fades once their body gets used to the medication, but if you experience acne that continues to be a problem, do not hesitate to reach out to your doctor