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Int J Biol Sci Mitochondrial SIRT2-mediated CPT2 deacetylation prevents diabetic cardiomyopathy by impeding cardiac fatty acid oxidation

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Food and Drug Administration (FDA) accelerated approval for treating metabolic dysfunction-associated steatohepatitis (MASH), the first GLP-1 approved for this indication Metabolic dysfunction-associated steatohepatitis (MASH), formerly known as nonalcoholic steatohepatitis (NASH), is a serious condition that occurs when fat accumulates in the liver, causing inflammation and damage, such as scarring (fibrosis), cirrhosis or liver failure