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PMID 12217902
NAD+/NADH redox alterations reconfigure metabolism and rejuvenate senescent human mesenchymal stem cells in vitro
10.1089/jmf.2016.0063 102 VatsyayanR.ChaudharyP.SharmaA.SharmaR.Rao LelsaniP
Most populations were conserved across species, with macaques expressing Calcr and Ramp3 in similar cell populations as rodents
NAPDH Oxidase converts oxygen to Super Oxide (O 2 ) mainly in neutrophils Myeloperoxidase (MPO) converts peroxide (H2O2) into Hydrochloric Acid (HOCl) mainly in neutrophils Fenton Reaction generates Hydroxide (OH-) from peroxide (H2O2) using iron Superoxide Dismutase (SOD) converts Super Oxide (O 2 ) to peroxide (H2O2) Glutathione convert Hydroxide (OH-) to water Catalase converts Peroxide (H2O2) to water We will see in the immunology section that that a defect in NADPH Oxidase causes Chronic Granulomatous disease
It reduces how much energy comes in by suppressing appetite, slowing digestion, and improving how the body handles the food that does get consumed
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