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tirzepatide activates the GIP and GLP-1 incretin receptors and adds a glucose-dependent insulin-secretion effect that an amylin analog does not have

Phinney DGM, Di Giuseppe J, Njah, et al

[13] [15] Rare but serious side effects include hypersensitivity reactions, such as urticaria, angioedema, or anaphylaxis, which require immediate medical attention

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However, side effects can occur, particularly with inappropriate dosing

Jurgensen M, Rapp M, Dohnert U, Frielitz F, Ahmed F, Cools M, Thyen U, Hiort O (2021) Assessing the health-related management of people with differences of sex development