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American Journal of Respiratory Cell and Molecular Biology , 48 (1), 1726
We provide evidence that GSH indeed plays a key role in disulfide bond formation and redox homeostasis in the periplasm: We observed that GSSG can complement for the loss of DsbA and, unexpectedly, that GSH accelerates disulfide bond formation in the presence of DsbA
A similar increased response of the PPP was found in the sea cucumber, Apostichopus japonicus , in response to estivation (when feeding stops), suggesting an increased carbon flow into the PPP, as an antioxidant mechanism 77
Bharathi Rajasridhar, board-certified plastic surgeon at The Aesthetic Studio