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Clin Rheumatol

doi: 10.3389/fnint.2013.00059 118 GoldgaberDHarrisHWHlaTMaciagTDonnellyRJJacobsenJSet al

Based on topical glutathione trials, visible changes in skin lightness (L* values) appeared by around 8-10 weeks

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When given orally, stomach acids and enzymes destroy glutathione before it is absorbed into the bloodstream