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Collectively, above evidence shows that natural products may serve as effective therapeutic agents in DKD management
In animal studies, DSIP demonstrated anxiolytic effects, reducing anxiety-like behavior in mice (Shekunova et al., 2002), and lowering plasma corticosterone levels in rats (Kovalzon et al., 1997)
Ethanol extract (SEL001), isolated from the potent probiotic strain Lactobacillus sakei proBio-65, has a protective effect on imiquimod-treated psoriasis-like skin inflammation in a mouse model, with decreased gene expression levels of IL-19, IL-17A, and IL-23 (Rather et al., 2018)
Drosophila CHIP protects against mitochondrial dysfunction by acting downstream of Pink1 in parallel with Parkin
Selected Research Highlights Metabolic Pathways: Multi-ingredient blends like Lipo-C are commonly referenced in formulation discussions involving energy metabolism, methylation support, and nutrient cofactor systems
peripheral vascular thrombosis Hematological : Polycythemia vera (a rare type of blood cancer) Gastrointestinal : Mild, transient diarrhea Dermatological : Itching
