HoffmannLa Roche, Roche Innovation Centre Basel, Basel, Switzerland
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In contrast, LPO levels showed a non-significant increase of 13.69% and significant increases of 73.29%, 104.79%, 264.38%, and 167.12%, respectively, compared to the control (Table 6)
Liraglutide-loaded microspheres have shown promise for sustained drug release over 1 month
Common adverse effects include gastrointestinal symptoms such as nausea (reported in 4050% of patients), vomiting, diarrhea, constipation, and abdominal discomfort
Symptoms typically peak during the first week and then gradually diminish