Heat stress in vitrified oocytes has an impact on the oocytes []
Discovery of human zinc deficiency: its impact on human health and disease
1), upregulating antioxidative defensive systems by increasing the expression or activity of antioxidant enzymes such as superoxide dismutase and glutathione peroxidase 23
Glutathione helps slow down aging by fighting harmful free radicals
Upregulation of Nrf2 is an adaptive mechanism in the absence of Cpt1a To evaluate the importance of Nrf2 in Cpt1a-deficient cells, we employed two potent inhibitors of Nrf2, Brusatol and ML385, with distinct mechanisms of action 54,55
The future lies in developing selective modulatorsboth inhibitors and potential activatorstailored to specific diseases and biological contexts, such as hormone-sensitive cancers, neuroinflammatory conditions, and metabolic syndromes