Critical Requirements : Do NOT use if pregnant Do NOT use if planning pregnancy within 2 months Stop medication at least 2 months before planned pregnancy (allows medication to clear system) If pregnancy occurs while taking medication, stop immediately and contact healthcare provider Contraception During Treatment : Women of childbearing potential must use effective contraception Tirzepatide (Zepbound) may reduce oral contraceptive effectiveness
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The drug may still offer important systemic benefits
It acts as an agonist at glucagon-like peptide-1 receptors, glucose-dependent insulinotropic hormone receptors, and glucagon receptors
Bjerregaard Jensen S, Sauerberg P, Nielsen FS, Pedersen BL, Skibsted E (2018) Tablet formulation comprising semaglutide and a delivery agent
Specific situations requiring medical advice include: consistently elevated blood pressure readings above 140/90 mmHg (or above the individual target set by their healthcare team), symptoms suggesting low blood pressure such as recurrent dizziness or fainting, or any new cardiovascular symptoms including chest pain, palpitations, or unusual shortness of breath