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In turn, phosphorylation of the adaptor proteins insulin receptor substrate 14 (IRS-14) and Shc leads to activation of the phosphatidyl inositol-3 kinase (PI3K), the mitogen-activated protein kinase (MAPK) and the 14-3-3 pathways (Baserga, 2000)

Although studies of MAMs in ovarian tissue remain limited, evidence from various tissue models suggests that MAMs integrity is critical for regulating cellular responses to oxidative stress, nutrient deprivation, and hormonal signals [124, 125]

The effect of GLP-1 medications varies by individual

2023, doi: 10.1007/s12630-023-02549-5

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