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Note: Tirzepatide for adolescents is considered off-label and evaluated on a case-by-case basis

While effective for immediate symptom resolution, this approach shuts down endogenous production by triggering a negative feedback loop

Encouraged by their success with the dual agonist, Tschp and DiMarchi wondered if it was possible to go a step further and develop a peptide to simultaneously target three key metabolically-related hormone receptors: GLP-1, GIP and glucagon

StatPearls notes that high-dose oral B has been shown effective for maintenance, but recommendations are to always use the parenteral route in severe neurological manifestations