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GLP-1 release from stomach and colon fragments incubated ex vivo Stomachs and colons of ND lean or HFD obese rats were collected after euthanasia, washed to remove the debris and then cut into small pieces
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(33896531) However, the added benefit of this additional dose is unclear
Early research suggested it promoted fat storage
We hope this has cleared up the confusion and provided a clear path forward
Based on Phase 2 trial data, retatrutide's side effect profile appears broadly consistent with other incretin-based therapies, though the addition of glucagon receptor agonism introduces some distinct considerations
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