Rybelsus (oral semaglutide) Prescribing Information
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Firstly, exogenous and endogenous GLP-1 is rapidly inactivated in vivo by dipeptidyl peptidase 4 (DPP-4), which recognizes Ala or Pro at the second position of the amino acid sequence of a peptide and removes dipeptides from the N-terminus [5-7]
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Set your prescribed dose following the manufacturer's instructions