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Depending on the population, 20% to 53% of individuals may have inherited one T copy (677C/T genotype), and 3% to 32% of individuals may have inherited two T copies (677T/T genotype) for the MTHFR gene (22)

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These symptoms are often linked to how GLP-1 medications affect digestion, and recognising personal triggers may help reduce discomfort and improve treatment tolerance

12 Therefore, since folate status modulates both genetic stability and DNA methylation, these critical indices are determined by both dietary intake and the activity of a number of folate metabolism enzymes, many of which exist in polymorphic form

Particularly, when paired with ongoing medical support

PMID: 90 YunCYanSLiaoBDingYQiXZhaoMet al