If you have known MTHFR mutations, a history of poor response to cyanocobalamin, or strong preference for methylcobalamin, seeking a formulation with that form is reasonable
Break the fast with a protein-rich meal (30-40g protein)
For prevention and treatment of vitamin B12 deficiency, cyanocobalamin in chewable, sublingual, or liquid forms (rather than in a multivitamin) is best under most circumstances
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This can help establish a baseline and potentially provide a boost to your weight loss or energy goals