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Importantly, the metabolic and behavioral abnormalities observed in male BBS5 / mice were recapitulated in females (Supplemental Figure 1, DJ), suggesting that there were no sex differences in disease manifestation

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They met four times (visits 25) for 1 hour each to discuss diet, exercise, and behavior modification based on recommendations in the Diabetes Prevention Program ( 2.4 Study outcomes All outcome measures were collected at baseline and after 20 weeks, with analyses adjusted for baseline values

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