Here are some common reasons a provider may recommend pairing B12 with tirzepatide: Patient is at a higher risk for vitamin B12 deficiency Patient has confirmed low B12 levels and is low in energy To monitor nutritional health during long-term GLP-1 treatment Important note: Vitamin B12 is not a weight-loss medication, nor does it enhance tirzepatides effects
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That means your body needs it to carry out lots of important functions, including (1, 2): Red blood cell formation DNA synthesis Brain and nervous system functioning Energy production (metabolism) Immune system health Risk Factors for Vitamin B12 Deficiency Your body doesnt produce B12 on its own
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A potential concern with dietary supplements is the lack of regulatory oversight
The honest caveat: most of this evidence is from cell and animal studies