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However, sustained HIF-1 activation in the context of neurodegeneration may exacerbate inflammation and promote A production, thereby worsening synaptic dysfunction and neuronal damage (Zhang et al., 2007)
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Its role as a key coenzyme in redox reactions makes it a subject of significant interest in cellular biology and metabolic pathway research
Crucially, an integrated, snRNA-seq-based comparison across 13 distinct PCD modalities established entotic cell death, apoptosis, necroptosis, and pyroptosis as the four dominant cell death pathways driving DKD progression (135)
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