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Pramlintide was the first-generation amylin analog with a short half-life (~50 minutes), requiring multiple daily administrations
Supports regeneration in areas affected by thinning or miniaturization
NFE2L2 and SLC25A39 drive cuproptosis resistance through GSH metabolism
92% of patients achieved more than 10% weight loss compared to 10% on diet and exercise counselling alone
Conclusion: Glutathione is safe, tolerable and effective whitening agent when used in topical cream (2%) and also in oral form in treatment of melasma.
& Bajus, A
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