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Given these potential mechanisms, this study was designed to test the hypothesis that DIO mice restored to the weight and adiposity of LD controls through NNMTi treatment and LD switch 13 have a similar microbiome profile to mice continuously maintained on LD

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10.2217/cer-2016-0059 122 WalshamA

Studies in animal models have shown it may help protect and repair the lining of the stomach and intestines, with research exploring its effects on gastric ulcers, inflammatory bowel conditions, and intestinal tissue damage

In current experiment, intra-articular injection of MIA allows for the induction of functional impairments and structural damage resembling OA 34,35