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It was first reported by Sawyer, Hruby, Hadley and colleagues in the Proceedings of the National Academy of Sciences in 1980, and it departs from native human alpha-MSH at only two of thirteen positions: norleucine replaces the oxidation-prone methionine at position 4, and the phenylalanine at position 7 is inverted to its D-enantiomer

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Plus, the expansion of sterile cartridge production capacity in Switzerland and sterile vial production capacity in the US are on track

Nature Communications , 14 , 2692