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GLP-1 receptor activation can modestly increase metabolic activity, which some patients experience as increased energy expenditure or changes in resting heart rate

Amino Acids, 41 (2), 507-515

Significant Findings and What They Mean To put it into perspective, for every 1,000 patients treated over a year, there were nine fewer cardiovascular deaths and 10 fewer cardiovascular events in those on GLP-1 medications

In peripheral tissues, GIP receptor activation in adipocytes promotes lipid storage under fed conditions but may facilitate lipolysis when insulin levels are low, a nuanced effect that remains an active area of investigation in metabolic research [5]

It turns out, that same PhD graduate subsequently used this knowledge to increase proanthocyanidin concentrations in the edible portion of white clover and ryegrass to improve livestock nutrition, and to reduce the environmental impact of agriculture