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Clinical trials evaluating semaglutide for both diabetes management (SUSTAIN trials) and weight loss (STEP trials) did not identify bruising as a frequent adverse event compared to placebo groups
Oral Activity of the Growth Hormone Releasing Peptides
Some have pivoted patients to compounded semaglutide as the primary GLP-1 offering
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The SELECT trial reported a 20% reduction in major adverse cardiovascular events with semaglutide versus placebo in patients with overweight/obesity and established cardiovascular disease, without diabetes [34] [35]
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