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Reduced food intake compounds the issue

The full interim commissioning guidance can be read here

For patients with Hashimoto's disease who also have obesity or type 2 diabetes, a comprehensive treatment approach addressing all conditions is appropriate

But its a very different proposition than to say, Drug X lowers your risk of a heart attack by 50%

References: Buckley ST et al (2018): Transcellular stomach absorption of a derivative glucagon-like peptide-1 receptor agonist

Randomized controlled trials that substitute UPFs with minimally processed or whole-food dietary patterns, such as the Mediterranean diet, could be useful in providing stronger therapeutic evidence by assessing the extent to which dietary modification may reduce the severity and/or mitigate the types of psychiatric presentations