AMPLITUDE-O Trial Investigators, Gerstein HC, Sattar N, Rosenstock J, Ramasundarahettige C, Pratley R, Lopes RD et al (2021) Cardiovascular and renal outcomes with efpeglenatide in Type 2 diabetes
Every vial is kept in temperature-controlled 20C freezers at our UK facility, from the moment it arrives through to dispatch protecting peptide stability and purity
Puhl et al., 2008
The big question is whether the health of the individual improved with that loss of body weight
However, DPP-4 inhibitors (such as sitagliptin or linagliptin) should be discontinued when initiating semaglutide, as both drug classes work through incretin pathways, and combined use offers no additional glycemic benefit while potentially increasing adverse effects
Using a lower volume of bacteriostatic water produces a more concentrated solution (smaller injection volume per dose)