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It acts as a dual agonist at amylin receptors (AMY1R, AMY2R, AMY3R, formed by calcitonin receptor heterodimerized with RAMP1-3) and calcitonin receptors, with structural modifications (e.g., N-terminal fatty acid acylation, proline substitutions) preventing fibril formation, enhancing stability, and enabling once-weekly dosing via albumin binding for prolonged circulation

Essential, yet not naturally found in the human body

When antigens from food, bacteria, or toxins come into contact with mast cells, the cells release mediators that cause various physiological responses, including inflammation

The combined product is supplied as a lyophilized (freeze-dried) powder in a vial containing both components

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Your healthcare provider will guide you through the process and ensure that you are comfortable while the treatment is being administered