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The SELECT cardiovascular outcomes trial established that semaglutide reduces major adverse cardiovascular events by 20%, providing a strong clinical rationale for treatment that extends beyond weight management alone

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N Engl J Med 2021;384:989-1002.ArticlePubMed 33

dopamine levels are modulated in response to GLP-1s

They boost how the body responds to insulin, slow down how the stomach empties create a sense of being full, and help keep blood sugar stable

They work by slowing gastric emptying, increasing feelings of fullness, and reducing appetite