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Pharmacokinetic characterisation is comparatively thin, but distribution and elimination have been profiled in rats and dogs in a 2023 pharmacokinetic study (PMC9794587), which is useful context because most claims about systemic healing rest on animal exposure data rather than validated human pharmacology

Its a marker, not a mechanism

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Both were removed from FDA 503A Category 2 on April 22, 2026, but neither is on Category 1 either

Patients should be trained on proper disposal of used needles in a sharps container and should never reuse needles due to infection risk and potential for needle damage that could cause pain or tissue trauma

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