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[PMID: 24565113] PubMed record related to this compound for laboratory literature review

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Isocitrate Dehydrogenase Mutations As indicated earlier, both IDH1 and IDH2 enzymes utilize NADP + as their cofactor and generate NADPH via oxidative decarboxylation of isocitrate outside the context of the TCA cycle

doi:10.1016/S2213-2600(23)00239-4 11

Its supplementation elevates NAD + , activating SIRT1 to regulate metabolism and suppress neuroinflammation ( 4.5 Limitations and future directions Limitations of the present study include incomplete recapitulation of human SAE heterogeneity by CLP and the lack of Nrf2 knockout/GSH inhibitor validation

Essential supply checklist Your supply list depends on whether you are using a pre-filled pen or drawing from a vial