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And then you can start doing things with it, whether its research or injecting it into yourself or loved ones. He calls the term research grade a euphemism

As in this group of patients B12 symptomology often is not recognized and the effect of oral supplementation regularly is insufficient (as a result of the destruction of intrinsic factor production, among other things), a large number of them suffer from B12 deficiency

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In women undergoing fertility treatments, a potentially life-threatening complication is ovarian hyperstimulation syndrome (OHSS), characterized by rapid weight gain, abdominal pain, ascites, and electrolyte imbalances

However, when very high oral doses are taken, approximately 1% can be absorbed through passive diffusion, independent of intrinsic factor, which explains how mega-doses can still raise serum levels