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PLoS One 3 , e2935 (2008)
How PRIME Medicine Helps Patients Manage Retatrutide Safely At PRIME Medicine in Corona Del Mar, CA, retatrutide therapy is supervised with a personalized approach to dosing, symptom management, and ongoing follow-up
95% CI, 0.25-0.5) and 13% less likely to be hospitalized (HR = 0.87
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Usage is especially high among women aged 50 to 64, while men catch up in older groups
Major Criteria Congenital multiple contractures, characteristically adduction-flexion contractures and/or talipes equinovarus (clubfoot) Characteristic craniofacial features, which are evident at birth or in early infancy Characteristic cutaneous features including skin hyperextensibility, easy bruisability, skin fragility with atrophic scars, increased palmar wrinkling Minor Criteria Recurrent/chronic dislocations Pectus deformities (flat, excavated) Spinal deformities (scoliosis, kyphoscoliosis) Peculiar fingers (tapering, slender, cylindrical) Progressive talipes deformities (valgus, planus, cavum) Large subcutaneous hematomas Chronic constipation Colonic diverticula Pneumothorax/ pneumohemothorax Nephrolithiasis/cystolithiasis Hydronephrosis Cryptorchidism in males Strabismus Refractive errors (myopia, astigmatism) Glaucoma/elevated intraocular pressure Myopathic EDS (mEDS) If a person meets the diagnostic criteria for mEDS, genetic testing should be done to confirm the diagnosis
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