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Targeted delivery of PROTAC-based prodrug activated by bond-cleavage bioorthogonal chemistry for microneedle-assisted cancer therapy

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Recently, we have published a pilot study in patients with LN on stable immunosuppressive treatment and non-immunosuppressive treatment with RAASi to whom a 10-mg dose of empagliflozin was added, obtaining a 50% reduction in residual proteinuria with minimal changes in eFGR and with few side effects (38)

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