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Unlike older GLP-1 medications that target only one hormone, tirzepatide is the first dual GLP-1 (glucagon-like peptide 1) and GIP receptor agonist that offers greater benefits, including stronger appetite suppression, deeper metabolic changes, and more significant weight loss

Both faced Eli Lilly lawsuits, and both offer similar glycine/B12 formulations

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Key Takeaways Tirzepatide can cause nausea by slowing gastric emptying, making large or heavy meals more likely to trigger symptoms