Myoglobin triggers ferroptosis in renal tubular epithelial cells, contributing to Crush Syndrome-associated acute kidney injury
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Therefore, regulation of intracellular GSH level is a promising strategy to boost the efficacy of antitumor treatment, as the exhaustion of antioxidants is highly desirable to sensitize cancer cells to various therapeutic means, such as chemotherapy, photodynamic therapy (PDT), chemodynamic therapy (CDT), and radiotherapy
For further information regarding WADAs approach to the routes of administration of glucocorticoids and washout periods, please refer to the Summary of Major Modifications and Explanatory Note
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