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In this way, ROS have at least an indirect impact on the quality of gametes and embryos

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Epithalon induces the expression and activity of telomerase reverse transcriptase in somatic cells, promoting elongation of telomeric DNA repeats at chromosomal termini

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Arginase activation, decreased NO, increased ROS resulting in endothelial dysfunction and vascular stiffness were also observed in wild-type mice exposed to cigarette smoke, in contrast to Arg-II knockout mice, suggesting that Arg-II contributes to smoking-induced vascular dysfunction [137]

Cushman, MD, professor of physical medicine and rehabilitation at the University of Utah Health