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In fact, several folate-requiring enzymes are actually inhibited by excess substrate ( 5 )
Common adverse reactions include arthralgia, injection site erythema, injection site pruritis, pain in extremity, peripheral edema, myalgia
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Although various attempts have been made to discover metabolite biomarkers for the diagnosis and treatment response of MDD, problems with sample size and consistency of results have limited clinical application
Berneis K, Rizzo M, Lazzaroni V, Fruzzetti F, Carmina E
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