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Frozen storage ( 20 C, and preferably lower for long-term): Recommended for extended timelines, with vials kept well sealed to limit moisture uptake and oxidative degradation

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Early treatment phases often require close attention, while stable patients may benefit from extended intervals and digital support

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They also built in parameters accounting for the fact that semaglutide, the key active ingredient in some leading GLP1RAs, is expected to lose patent protection around 2032, which could bring substantial price reductions

Given this scenario, endocrinology should see a lot of pathbreaking drugs in the coming years