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Abstract Glutathione is a tripeptide synthesized at cytosolic level, that exists in cells in a reduced form (thiol-reduced-GSH-) and in an oxidized form (disulfide-oxidized)

This blocking of tumor growth by agonists of GH-RH, which at first may seem paradoxical, appeared to be caused mainly by the downregulation of the pGHRH-Rs and tumoral GH-RH-Rs

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21,22 Both ESCC and EAC are currently treated with multimodal approaches, and the development of various novel therapeutic agents is flourishing

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