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Cell culture applications utilize concentrations of 10-50 M for effective senescent cell elimination, with administration durations typically 24-72 hours depending on experimental objectives and cellular models

In both groups, lixisenatide markedly ameliorated neurological deficit, reduced infarct volume, along with inhibited the expression of oxidative stress parameters (GSH, MDA, NO and catalase enzyme), apoptotic marker (caspase-3), and inflammatory factor (TNF-) in ischemic brains of rats (117)

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In addition, mice that were already obese lost weight, gained strength and increased their lean body mass on a weekly dose of prednisone despite eating a high-fat diet