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Participants receiving the maximum tolerated dose of Zepbound, combined with diet and exercise, experienced an average body weight loss exceeding 20% over 36 weeks, with sustained and additional weight loss observed in ongoing treatment

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Simultaneously, these medications suppress glucagon secretion, a hormone that raises blood glucose levels

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This means an unrefrigerated dose could deliver less peptide to your GLP-1 receptors, reducing appetite suppression and metabolic benefits

Tirzepatide consistently produces stronger weight loss outcomes in clinical research