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Common adverse effects include paraesthesia or tingling (2025% of users), dry mouth (20%), constipation (1517%), altered taste, insomnia, and cognitive difficulties with concentration and memory

With the constant usage, the complexion becomes significantly fairer and smoother

However, enzyme supplements may cause their own gastrointestinal side effects that can overlap with GLP-1-related symptoms, and some formulations containing bromelain or papain may interact with anticoagulants

Educate patients about risks