The effect of glucagon-like peptide-1 (GLP-1) receptor agonists in persons with obesity and knee osteoarthritis in this population has not been well-established. To test the impact of a GLP-1 receptor weight loss medication on knee OA outcomes, Bliddal and colleagues conducted a double-blind, randomized, placebo-controlled trial at 61 sites across 11 countries
At the 1.2 mg daily dose , a pen lasts about 15 days
Went from 158 to 139 to 154, although this took months and was not immediate
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This means the bodys normal feedback mechanisms stay intact
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