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[6] [7] The GIP component may complement GLP-1 activity by supporting insulin secretion and potentially influencing fat metabolism, though the precise contribution of GIP agonism in humans remains an area of active research and the evidence is not yet fully established
13, 20, 26, 27, 48, 70, 71, 72 They are actively taken up into the brain 73 and can affect diverse physiological processes such as cell signaling, 71 neurotransmitter synthesis and release, 70 mitochondrial function, 20 lipid metabolism, 13, 74 immune function, 75 cellcell interactions 76 and gene expression
Exenatide extended-release has been shown in studies to cause thyroid tumors in animals, but it's not yet known if it can cause thyroid cancer in people
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